KIDNEY AND BONE HEALTH

Kidneys play a key role in keeping you healthy, working around the clock to remove waste from your blood. That’s why it’s so important to take care of them, especially if you have HIV-1. Ask your healthcare provider how HIV-1 medicines can impact your kidneys.

Less impact on kidney lab tests:

In clinical studies, GENVOYA® had less impact on kidney lab test results than the other approved HIV-1 treatments.*

It is not known if these lab test results predict long-term kidney health.

In clinical studies, less than 1% of adults had to stop taking GENVOYA due to kidney-related issues.

GENVOYA may cause new or worse kidney problems, including kidney failure. Your healthcare provider should do blood and urine tests to check your kidneys before you start and while you are taking GENVOYA. Your healthcare provider may tell you to stop taking GENVOYA if you develop new or worse kidney problems.

*The other treatments in these studies were STRIBILD, ATRIPLA, or TRUVADA + Reyataz + cobicistat or ritonavir.

Getting to undetectable and increasing your CD4 T-cells are key treatment goals. Because HIV-1 medicines may impact your bones, it’s also important to protect your bone health. If you’re under 30 years of age, you’re still developing bone mass. If you’re over 30, your bones have fully developed and it’s important to try to maintain them.

Less impact on bone mineral density:

In clinical studies, GENVOYA® had less impact on hip and lower spine bone mineral density than the other approved HIV-1 treatments.*

The long-term effect of these changes on bone health is not known.

Your healthcare provider will need to do tests to monitor your health before and during treatment with GENVOYA. In clinical studies, the most common side effect of GENVOYA was nausea.

*The other treatments in these studies were STRIBILD, ATRIPLA, or TRUVADA + Reyataz + cobicistat or ritonavir.

GENVOYA is FDA-approved for people with mild-to-moderate kidney problems and can be used in some people with lowered kidney function without changing the dose.

GENVOYA is FDA-approved for people with mild-to-moderate kidney problems and can be used in some people with lowered kidney function without changing the dose.

Ask your healthcare provider how to be proactive about your bone health.

Ask your healthcare provider how to be proactive about your bone health.

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about GENVOYA?

GENVOYA® may cause serious side effects:

Who should not take GENVOYA?

Do not take GENVOYA if you take:

What are the other possible side effects of GENVOYA?

Serious side effects of GENVOYA may also include:

The most common side effect of GENVOYA is nausea. Tell your healthcare provider if you have any side effects that bother you or don't go away.

What should I tell my healthcare provider before taking GENVOYA?

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call .

What is GENVOYA?

GENVOYA is a 1-pill, once-a-day prescription medicine used to treat HIV-1 in people 12 years and older and weigh at least 77 lbs. It can either be used in people who are starting HIV-1 treatment and have never taken HIV-1 medicines before, or people who are replacing their current HIV-1 medicines and whose healthcare provider determines they meet certain requirements. These include having an undetectable viral load (less than 50 copies/mL) for 6 months or more on their current HIV-1 treatment. GENVOYA combines 4 medicines into 1 pill taken once a day with food. GENVOYA is a complete HIV-1 treatment and should not be used with other HIV-1 medicines.

GENVOYA does not cure HIV-1 infection or AIDS. To control HIV-1 infection and decrease HIV-related illnesses, you must keep taking GENVOYA. Ask your healthcare provider if you have questions about how to reduce the risk of passing HIV-1 to others. Always practice safer sex and use condoms to lower the chance of sexual contact with body fluids. Never reuse or share needles or other items that have body fluids on them.

Please see Important Facts about GENVOYA, including Important Warnings.